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Skeletor
The main villain from “He-Man and the Masters of the Universe,†Skeletor had a perfect evil laugh and a bunch of weird friends, such as Beast-Man, Trap Jaw, and Clawful. After his face was melted off by magical acid, he adopted the new name, but never really learned to wear more clothes to protect himself.
Scar
Aku
Discord
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Big Bad Wolf
Krang
Hydra
The Joker
A famous antagonist in the DC Animated Universe, The Joker served as the main antagonist in many Batman movies and cartoons. After he was knocked into a chemical vat at the Ace Chemicals Factory, he turned into a ruthless, sadistic maniac with white skin, green hair, and bright red lips.
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The Blockheads
Vegeta
Extremely vain and determined to win at all costs, Vegeta is the popular manga character created by Akira Toriyama. Later in the series, he reluctantly unites with others, becoming an antihero, and later, he acts like one of the heroes.
Bluto
Brain
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Dr Claw
HIM
Even though this demon is very weird-looking (by the way, does anyone know why he is wearing a Santa Claus-like dress and high heels?), he can be really dangerous!
Cobra Comander
Hector Con Carne
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Who is this cartoon villain?
Gargamel
Don Karnage
Sideshow Bob
This evil villain from "The Simpsons" can be both smart and naive. Even though he graduated from Yale University, he worked as a non-speaking sidekick on Krusty the Clown's TV show and hated his job with all his heart. He was later ent to prison for an attempt to frame his co-worker for robbery.
Dr Doom
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The Greasers
Claw
Kingpin
Aku
Meet Aku - the main antagonist of Samurai Jack. While he doesn't look too scary, he is an evil demon who ruled the world for centuries. You probably also remember the daughters of Aku - seven human-demon hybrid women, whose main purpose in life was to kill Samurai Jack.
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Frieza
Even though there are a few main villains in the Dragon Ball Z and Dragon Ball Z Kai, Frieza (sometimes also spelled as Freeza) is arguably the main antagonist of the entire manga series. While other villains in the Dragon Ball manga series are simply killing machines created to destroy, Frieza is an independent, knowledgeable being, who kills only when he wants to.
Baron Greenback
The Duke
Shredder
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Megatron
Feathers McGraw
Mr. Burns
Charles Burns, voiced by Harry Shearer, appears a lot in the animated TV series, "The Simpson." He is an embodiment of popular stereotypes about corporate America, so this elderly man is greedy, selfish, cruel, and cares only about money.
Krang
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Who is this cartoon villain?
Plankton
The Ice King
Did you know that the real name of The Ice King (yes, the one who can create and manipulate ice) from the TV series, "Adventure Time," is Simon Petrikov? No wonder the former main antagonist of "Adventure Time" prefers to be called The Ice King instead.
The Red Guy
Mojo Jojo
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Who is this cartoon villain?
Black Pete
Megatron
Megatron was not always a powerful and evil machine. In many ways, he is a fallen hero, who started in the oppressed lower working castes and ended up as an incredibly strong and brutally direct leader of the Decepticons.
Lex Luthor
Piccolo
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Who is this cartoon villain?
Dr. Sivana
Simon Sinister
Captain Hook
Harley Quinn
Many people know her only as the Joker's girlfriend, but Harley Quinn is a smart and powerful super-villain on her own. She first appeared in "Batman: The Animated Series" in 1992, and since then, this crazy girl has been a recognizable figure in the DC Universe.
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Apocalypse
Apocalypse (or En Sabah Nur - "the First One") is one of the first mutants. This well-known supervillain in the Marvel Universe first appeared in comic books only, as a member of the original X-Factor team. He later became a part of the X-Men movies as well as some related spin-off teams.
Skelator
Hordak
Team Rocket
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Joker
Wile E. Coyote
Yosemite Sam
Amon
He has many names, including the Dark Voice, the Fallen One, and the Dark God, but he is mostly known as Amon - the charismatic, smart, mysterious leader of an anti-bender revolutionary group, The Equalists.
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Dr. Zin
Gargamel
This evil wizard, who is always accompanied by his cat, is one of the main characters of the Smurfs comic books and the Smurfs cartoons. He hates Smurf with all his heart and dreams about the world without them. However, his attempts to destroy Smurfs are usually unsuccessful.
Zim
Hector Con Carne
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Who is this cartoon villain?
Brain
Stromboli
Plankton
Plankton is a smart copepod who runs the Chum Bucket, which is not as successful as Krusty Krab restaurant, along with Karen, a talking supercomputer. They are married, and even though they love each other, they fight a lot because Plankton had never given Karen a gift for their anniversary and doesn't help her much. In one of the episodes, Plankton learns from SpongeBob that he has to show his love.
Maleficent
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Bluto
Do you remember that big guy in bright yellow pants? Yes, that's Bluto (or Brutus) - a both fun and mean character who first appeared in the Thimble Theatre comic strip in 1932. The next year, Bluto the Terrible became the main antagonist of the animated cartoon series, "Popeye."
Cruella De Vil
Diablo
Shere Khan
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Who is this cartoon villain?
Prince John
Brain
The two main character of the animated TV series "Pinky and the Brain" are genetically enhanced laboratory mice, who both live in the same research facility. While Pinky is generally nice and good-natured, his selfish and mean pal, Brain, always has some evil plan.
Dick Dastardly
Ursula
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Who is this cartoon villain?
Dr. Claw
The classic cartoon ran original episodes for only three seasons (1983-1986), but is well known to a few generations of kids. Evil scientist Dr. Claw tried to win Inspector Gadget and take over the world in almost every episode, but all his attempts were unsuccessful. At the end of an episode, he usually says his catchphrase "I'll get you next time, Gadget!"
Scar
Jafar
Hans
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Dr. Doom
Before he became the super villain you know as Doctor Doom, Victor von Doom was the Monarch of a small European country. He was a genius who, after discovering his mother's artifacts (and his mother was a witch), started practicing magic. Traditionally, he is also the archenemy of the Fantastic Four.
Turbo/King Candy
Captain Hook
HIM
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Deadpool
Duke
Duke Weaselton is a mean, greedy, and selfish crook from Disney's cartoon, "Zootopia." Like any villain, he is mean, extremely snide, and ready to betray anyone he knows. While he is a minor antagonist, his sense of humor makes him a pretty recognizable character in "Zootopia."
Dr. Facilier
Claude Frollo
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Who is this cartoon villain?
The Evil Queen
Evilla Cruella
Krang
The creepy brain of an evil alien from another dimension is one of the main antagonists in Teenage Mutant Ninja Turtles-related media, including cartoons, movies, books, merchandise, and comics. This supervillain was once a strong, feared, and powerful warlord from Dimension X, another universe where the wars never stopped.
Scar
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Ursula
Jafar
Shere Khan
Mojo Jojo
This dangerous monkey is the former pet of Professor Utonium and its main goal is to destroy the Powerpuff Girls. In each episode, this evil monkey mastermind has a new plan, from trying to get the girls to eat an evil pizza, to teaming up with other villains.
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Who is this cartoon villain?
Clayton
Black Pete
Pete is one of the oldest Disney characters - he was created by Walt Disney himself, who was the character’s original voice. This Disney villain can be seen everywhere from video games to Disney television shows, such as “DuckTales,†“Goof Troop,†and “House of Mouse."
The Sheriff of Nottingham
Gaston
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Madame Medusa
Captain Hook
Wile E. Coyote
He and the Road Runner are a hilarious duo that appeared a lot in the Looney Tunes and Merrie Melodies series of cartoons. The cartoon was originally created to parody chase cartoons like "Tom and Jerry," but quickly became popular on its own.
Mumm-Ra
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Davy Jones
Chairface
Cobra Commander
Zim
Zim, or Invader Zim, is the supervillain of the franchise of the same name. While he is rather an unsympathetic character, he can be also kind and understanding. Zim serves the Irken Empire, but because of his incompetence, he was forever banished to Earth. However, he thinks he was sent to Earth to conquer it.
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Who is this cartoon villain?
Hades
Dr. Zin
The main enemy of Dr. Benton Quest and his son, Dr. Zin is a main villain in Hanna-Barbera's 1960s "Jonny Quest" series and a mastermind behind the evil plans to steal and use Dr. Quest's inventions and ideas. His main goal? World domination, of course!
Kaa
Queen of Hearts
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Who is this cartoon villain?
Shan-Yu
McLeech
Ratigan
Venom
First a supervillain, now more of an antihero from Marvel comics, Venom is getting his own movie in 2018. He appeared a lot in Spider-Man comics, books, and movies.
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Who is this cartoon villain?
Lord Scum
The mysterious SCUM Lord first appeared in the animated television series, "James Bond Jr.," in the '90s. He later was also a protagonist in James Bond comic-book series, books, and a video-game. The villain, clearly inspired by Ernst Stavro Blofeld, is still one of the series's primary antagonists.
Governor Ratcliffe
Iago
Skinner
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Who is this cartoon villain?
Lucifer
Anton Ego
The imperious, hard-to-please Anton Ego is famous for his bad reviews that can destroy any restaurant's reputation. This food critic from the animated movie, "Ratatouille," is very specific and if he doesn't like what he is eating, he simply doesn't swallow.
Spidra
Chick Hicks
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Who is this cartoon villain?
Sir Hiss
The Shredder
Meet a master of Ninjutsu an arch-enemy of Splinter and the Ninja Turtles. The Shredder is one of the two main antagonists of the series; in one episode, he became a dangerous Super Mutant.
Banzai
Ed
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Who is this cartoon villain?
Madam Mim
Mother Gothel
Mumm-ra
An undead evil wizard and an absolute master of magic, Mumm-ra possesses unlimited knowledge and can transform into a more powerful, muscular creature. It makes him a super-dangerous enemy of the ThunderCats.
Hopper
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Who is this cartoon villain?
Stinky Pete
Lotso
Syndrome
General Woundwort
This intimidating rabbit, who is almost as big as a hare, appeared in the book, "Watership Down," movie, and TV series of the same name. General Woundwort has one blind eye, sharp teeth, prominent claws, and dark circles under both eyes.
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Who is this cartoon villain?
SkullMaster
Both a warrior and sorcerer, SkullMaster destroys everything in his way, including at least two civilizations - the Lemurians and the Atlanteans. Despite his generally unimpressive name, he is one of the most terrifying villains in the world of cartoons.
Bowler Hat Guy
Gaston
Jafar
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Big Bad Wolf
ScarFace
This terrifying puppet is controlled by the Ventriloquist, who uses ScarFace to commit crimes in the Batman movies or comics. He also occasionally appears in video games, such as Batman: Arkham Asylum, but not as a main villain.
Claude Frollo
Hades
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Who is this cartoon villain?
Doctor Facilier
Lady Tremaine
Scar
Ursula
Ursula, whose name means "bear" in Latin, is a plump cecaelia with six black octopus-like tentacles. After appearing in Disney's 1989 animated feature film, "The Little Mermaid," she became one of the franchise's main characters. Her main rival is King Triton because she dreams of ruling the city of Atlantica, as well as all the ocean.
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Who is this cartoon villain?
Queen Beryl
Queen Beryl is one of the main villains in the series, who has appeared in every continuation of the series, every book, video game, or movie. Her appearance was completely different before she became Queen of the Dark Kingdom, but now she has bright, long, red hair, pale skin, and dull orange eyes.
Sid Phillips
Stromboli
Yzma
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Who is this cartoon villain?
Ratcliffe
Angelica
Greedy, spoiled, and selfish Angelica Pickles is the main antagonist in the popular animated TV series, "Rugrats." She loves to bully the babies and is generally a spoiled girl who loves attention.
Sykes
Maleficent
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Who is this cartoon villain?
Madam Mim
Hopper
Majin Buu
Dishonest John
Always dressed in black, John is a stereotypical villain of Beany and Cecil, who always tries to foil their adventures. You probably remember his signature catchphrase : "Nya-ah-ãhh!"
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Who is this cartoon villain?
Doctor Facilier
Queen Beryl
Cruella De Vil
Mean and self-centered Cruella De Vil is obsessed with fashion. In attempt to create a unique coat for herself, she tires to get the skins of 99 Dalmatian puppies. She is among the most critically-acclaimed and recognizable Disney characters of all time.
Lady Tremaine
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Dick Dastardly
Partly inspired by actor Terry-Thomas, partly by Professor Fate (a comic villain in the movie, "The Great Race"), Dick Dastardly made an appearance in different cartoons by Hanna-Barbera Productions, but he is mostly known as a main character of the "Wacky Races" and its spin-off. This villain is always accompanied by his partner - a hilarious dog named Muttley who had a recognizable wheezy laugh.
Jafar
Hades
Gaston
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Megavolt
Magneto
This powerful mutant has many superpowers and superhuman abilities, but his most notorious one is the ability to generate and control magnetic fields. He is a well-known villain in Marvel comic books, mostly the X-Men series.
Venger
Chairface
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Who is this cartoon villain?
Lady Tremaine
Duke Nukem
Chairface
This man literally has a wooden chair for a head, and he is probably the weirdest villain ever. Chairface Chippendale appeared a lot in Tick comics, as well as a 1994 cartoon. His last name is in reference to the famous furniture brand of the 1800s.
Condiment King
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Who is this cartoon villain?
Majin Buu
Megatron
Madame Medusa
Cobra Commander
A character from "A Real American Hero" and the "G.I. Joe vs. Cobra" series, Cobra Commander appeared in the toyline, a bunch of comic books, and the cartoon series. Not much is known about this mysterious leader of the terrorist organization, but we know a lot about how he works and thinks. Cobra Commander has deliberately started political and social conflicts in various areas and his main goal is world domination.
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Who is this cartoon villain?
Horned King
Majin Buu
At first, he was known as an Innocent Buu. He was the result of Kid Buu absorbing the Grand Supreme Kai. He became Good Buu or simply Majin Buu as the result of the Innocent Buu splitting into good and evil halves. Sounds complicated, but the Dragon Ball manga series was never simple.
Krang
Brain
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Who is this cartoon villain?
Queen Grimhilde
Mumm-Ra
Megavolt
Megavolt is the main villain from Darkwing Duck and DuckTales. He was always a nerd, and when something went wrong during one of his a static-electricity experiments, he became infused with electricity. He can shoot it at any target he chooses. While this is his main power, he also has a weakness - Megavolt shorts out completely when he comes in contact with water.
Dr. Claw
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Lotso
Venger
Meet the main villain from the Dungeons & Dragons cartoon - he is a powerful evil wizard with bat-like wings and a single horn on the left side of his head. Venger wants to rule the world. To achieve this, he collects the magical artifacts given to the heroes by the Dungeon Master.
Shan Yu
Sykes
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Who is this cartoon villain?
Sid
Duke Nukem
Stinky Pete
A cute vintage pull-string toy from the '50s, with a pick axe and a gold pan, Stinky Pete is the main antagonist of "Toy Story 2." Nobody wanted to buy him, so he spent years in a toy store.
Henry J. Waternoose III
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Who is this cartoon villain?
Condiment King
Partially parody, partially the most notorious criminal ever, The Condiment King was created as a comic relief within "Batman: The Animated Series." This hilarious villain first appeared in the episode, 'Make 'Em Laugh.'
Syndrome
Chick Hicks
Chef Skinner
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Charles Muntz
Mor'du
Darla Sherman
Yosemite Sam
Even though he can look nice and even innocent at times, Yosemite Sam is the one of the main villains in Bugs Bunny. The name of this short, evil villain with a bright red mustache was inspired by Yosemite National Park.
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Who is this cartoon villain?
Hopper
Frollo
Team Rocket
It's not just a single villain, it's a crime syndicate that consists of Jessie, James, and Meowth, and is headed by Giovanni, also known as Viridian City Gym Leader. In the Pokemon world, the Team Rocket trio, sometimes abbreviated as TRio or JJM, is well-known for stealing the most powerful and rare Pokemon in the hopes of taking over the world.
Firebird
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